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Ongoing Fundings

Grant Type
Project Title
Amount
Start Date
Completion Date
Principal Investigator
National Key Research and Development Program (2022YFA0806100)
Mechanisms of metabolic reprogramming mediated by inter-organ molecular dialogue through epigenetic regulation
9,100,000RMB
01/12/2022
30/11/2027
Prof. Aimin XU
Area of Excellence (AoE/M-707/18)
Institute of Metabolic Medicine
77,803,000.00
30/04/2019
29/04/2027
Prof. Aimin XU
GRF (17114924)
CUB Domain-containing Protein 1 as a Novel Mediator of Nonalcoholic Steatohepatitis: Molecular Mechanism and Therapeutic Implications
1,553,537 HKD
27/06/2024
27/06/2027
Prof. Aimin XU
GRF (17107124)
B-Klotho as a novel anti-ageing factor by suppressing adipose senescence
$1,057,481
27/06/2024
27/06/2027
Dr. Leiluo GENG
GRF (17117724)
Semaphorin 6B as a novel glucose-lowering hormone to counteract type 2 diabetes: molecular mechanism and clinical implications
$1,558,606
27/06/2024
27/06/2027
Dr. Baile WANG
Investigator-initiated study (IIS) by Ferring Pharmaceuticals Limited
Prevention and management of preeclampsia-related preterm labour through targeting gut microbiome
$90,000
31/08/2023
31/08/2024
Dr. Yao WANG
Natural Science Foundation of Guangdong Province
Role of carbohydrate cycling diet in obesity and energy expenditure and underlying molecular mechanisms
RMB100,000
31/12/2022
30/12/2025
Dr. Leiluo GENG
HKSTP Ideation
OBpharm Limited
$100,000
31/07/2023
30/07/2024
Dr. Yu WANG
Young Scientists Fund of the National Natural Science Foundation of China (NSFC) (Project ref.:82200893)
Gut microbiome regulates soluble IL-6 receptor production to determine exercise responsiveness in terms of insulin sensitivity and glycemic control
$350,000
31/12/2022
30/12/2025
Dr. Yao WANG
Contract Research
同仁堂洋參三七丸調節幹細胞線粒體功能促進中風後神經再生及功能修復研究
$1,150,000
31/05/2023
30/05/2025
Prof. Jiangang SHEN
General Research Fund (GRF) (Project ref.:17120022)
Bone marrow adipose tissue orchestrates hematopoiesis to facilitate type 2 immune response during cold-induced beiging of white adipose tissue
$1,180.022
31/12/2022
30/12/2025
Dr. Baile WANG
General Research Fund (GRF) (1 Project ref.:7126523)
Elucidating roles of adaptor protein APPL2 in inhibiting adult neurogenesis via affecting mitochondrial function, redox signaling and mitochondrial dynamics in ischemic stroke with hyperglycemia
$1,194,296
30/09/2023
29/09/2026
Prof. Jiangang SHEN
Contract Research
安宮牛黃丸調控缺血腦卒中腸道菌群和神經保護機制研究
$1,245,000
31/05/2023
30/05/2025
Prof. Jiangang SHEN
University Research Committee- URC
A novel Role of Stanniocalcin-2 in the Regulation of Insulin Secretion from Pancreatic β cells
$1,379,053.00
31/12/2022
30/12/2025
Prof. Aimin XU
Health and Medical Research Fund (Project ref.:10212056)
Mapping the human gut mycobiome for the metabolic benefits of exercise in diabetes prevention
$1,399,160
30/06/2023
29/06/2026
Dr. Yao WANG
Health and Medical Research Fund (Project ref.:09201296)
Branched-chain amino acids mediate the crosstalk between gut microbiome and adipose tissue to induce metabolic inflammation (Project no.: 09201296)
$1,432,160.00
31/12/2022
30/12/2025
Prof. Aimin XU
Croucher Summer Courses
Arterial Ageing: from Mechanisms to Applications
$1,800,000
13/08/2023
12/08/2028
Dr. Yu WANG
NSFC Excellent Young Scientists Fund (Project ref.:82222903)
Photoresponsive drug delivery systems
RMB 2,000,000
31/12/2022
30/12/2025
Dr. Weiping WANG
Hong Kong Sports Institute: Sports Science and Research Funding Scheme
Development of an Evidence-Based Nutritional Intervention Targeting the Gut Microbiota to Improve Athletic Performance
$4,271,000.00
14/04/2023
13/10/2024
Prof. Aimin XU
广东省自然科学基金-面上项目 (2021A1515010841)
Th17激活在运动干预防治糖尿病效果中的作用及其机制研究
$ 125,600 HKD
31/12/2020
30/12/2023
Dr. Yan LIU
国家自然科学基金青年项目(32000816)
脂肪组织葡萄糖转运蛋白GLUT1对成纤维细胞生长因子21的调控
¥240,000 CNY
31/12/2020
30/12/2023
Dr. Leiluo GENG
国家自然科学基金青年项目(82000832)
机械敏感离子通道Piezo1通过调控骨髓脂肪细胞形成对全身代谢的作用及机理研究
¥240,000 CNY
31/12/2020
30/12/2023
Dr. Baile WANG
General Research Fund (GRF) (17127121)
Does Hippocampus Modulate Central Auditory Processing? A Functional MRI Study
$ 1,351,372 HKD
31/08/2021
30/08/2024
Prof. Ed Xuekui WU
General Research Fund (GRF) (17102920)
TRIF as a novel regulator of lipid droplet enlargement in visceral adipocytes
$1,125,732 HKD
31/08/2021
30/08/2024
Dr. Connie Wai Hong WOO
General Research Fund (GRF) (17117320)
The mechano-sensitive ion channel Piezo1 balances the conversion of mesenchymal stem cells to osteoblasts and bone marrow adipocytes
$ 1,195,542 HKD
31/12/2020
30/12/2023
Prof. Aimin XU
CAS - Croucher Funding Scheme for Joint Laboratories
Discovery and Development of Innovative Antibody Drugs for Metabolic and Cardiovascular Diseases
$ 3,750,000 HKD
28/02/2021
28/02/2024
Prof. Aimin XU
国家自然科学基金-面上项目 (82070860)
成纤维细胞生长因子21在运动改善糖尿病心肌病过程中的作用机制研究
¥690,800 CNY
31/12/2020
30/12/2024
Prof. Aimin XU
MERCK SHARP & DOHME (ASIA) LTD
Identification of metabolic factors involved in NASH progression in morbidly obese
$482,686 USD
15/11/2020
14/11/2023
Prof. Aimin XU
Early Career Scheme (ECS) (27115220)
Low-irradiance red light-triggered drug release for the treatment of retinoblastoma
986,520.00
31/08/2020
30/08/2023
Dr. Weiping WANG
HMRF (07181936)
Development of photo-targeted nanocarriers for esophageal cancer therapy
1,405,630.00
31/08/2020
30/08/2023
Dr. Weiping WANG
GRF (17118619)
Prostaglandin E receptor subtype 4 protects against diabetic cardiomyopathy by modulating cardiac fatty acid metabolism via FOXO1/CD36 signaling
1,157,363.00
31/12/2019
30/12/2022
Dr. Zhengyuan XIA
HMRF (07182836)
Role of the mechano-sensitive ion channel Piezo1 in the regulation of obesity and adaptive thermogenesis: molecular mechanisms and clinical implications
1,482,400.00
31/03/2020
30/03/2023
Dr Baile WANG
HMRF (07182516)
ANNEXIN A8 as a novel adipokine mediating visceral obesity-associated metabolic complications
1,484,540.00
15/07/2020
14/07/2023
Dr. Xiaoyan HUI
HMRF (07182726)
Implementation of multi-biomarkers algorithm for detection in Chinese obese individuals with non-alcoholic fatty liver disease
1,497,244.00
30/06/2020
29/06/2023
Dr. Kwan Yui Cynthia CHEUNG
GHP/138/18SZ
Shenzhen-Hong Kong United Network on Cardiovascular Disease (SHUN-CVD)
4,136,901.00
29/12/2019
29/12/2021
Prof. Bernard Man Yung CHEUNG
GRF (17124718)
Endothelial SIRT1 - a key circadian regulator controlling the 24-hour rhythmicity in blood pressure and energy metabolism
1,486,164.00
31/12/2018
30/12/2021
Dr. Yu WANG
GRF (17121520)
Androgen regulates white adipose tissue remodelling via suppression of PRDM16
1,145,727.00
31/12/2020
30/12/2023
Dr. Xiaoyan HUI
GRF (17121819)
The Single Transmembrane Protein β-klotho as a Novel Regulator of Insulin Secretion in Pancreatic β-cells
1,684,895.00
31/12/2019
30/12/2022
Prof. Aimin XU
GRF (17117320)
The mechano-sensitive ion channel Piezo1 balances the conversion of mesenchymal stem cells to osteoblasts and bone marrow adipocytes
1,195,542.00
31/12/2020
30/12/2023
Prof. Aimin XU
E-HKU703/20
Targeting Gut Microbiota for Non-alcoholic Fatty Liver Disease
1,691,843.00
30/09/2020
30/08/2020
Prof. Aimin XU
Guangdong-Hong Kong Technology Cooperation Funding Scheme
Development and Preclinical Evaluation of a A-FABP Neutralizing Monoclonal Antibody for Ischemic Stroke Treatment
1,327,458.00
31/08/2019
30/08/2021
Dr. Ruby Lai Chong HOO
HMRF (17123718)
Deletion of Telomere-Rap1 increases the susceptibility to myocardial ischemia/reperfusion injury via p53-PGC1α signaling during aging
868,463.00
31/12/2018
30/12/2021
Dr. Zhengyuan XIA
HMRF (81803769)
Hydrogen sulfide-responsive small-molecule nanoparticles as drug delivery carriers for cancer therapy and diagnosis
263,760.00
31/12/2018
30/12/2021
Dr. Weiping WANG
GRF (06173456)
Development of ultrasound-responsive polymeric nanoreactors for retinoblastoma therapy
1,499,628.00
31/07/2019
30/07/2022
Dr. Weiping WANG
HMRF (06172266)
Exploring the role of microRNA in sight-threatening diabetic retinopathy in Chinese patients with type 2 diabetes
1,499,956.00
31/07/2019
30/07/2022
Dr. Yu Yan CHEUNG
HMRF (06172636)
Targeting G protein-coupled receptor 110 for the treatment of obesity and non-alcoholic fatty liver disease
1,399,248.00
29/04/2019
29/04/2022
Dr. Zhe HUANG
GRF (17105318)
Neutrophil serine proteases as the endogenous suppressors of white adipose tissue browning and adaptive thermogenesis
775,656.00
31/12/2018
30/12/2021
Dr. Ruby Lai Chong HOO
HMRF (06172646)
Mitochondrial protein coiled-coil-helix-coiled-coil-helix domain 10 (Chchd10) as a novel factor for the treatment of obesity and its related diseases
982,396.00
31/05/2019
30/05/2021
Dr. Ruby Lai Chong HOO
GRF (17101819)
Syndecan-4 (Sdc4) as a key regulator of white adipose tissue browning for energy expenditure
1,113,341.00
31/12/2019
30/12/2022
Dr. Ruby Lai Chong HOO
NSFC Young Excellent Scientist fund
Mechanistic study of adipose browning
1,300,00.00 (RMB)
31/12/2019
31/12/2022
Dr. Xiaoyan HUI
GRF (17123419)
Thyroid hormone induces facultative thermogenesis in white adipose tissue through UCP1-independent mechanism
957,916.00
30/09/2019
29/09/2022
Dr. Xiaoyan HUI
HMRF (06172346)
AMPK γ2 as a master regulator of adipokine transcription: biological function, molecular mechanism and clinical implications
1,449,248.00
15/09/2019
14/09/2022
Dr. Xiaoyan HUI
GRF (17124420)
Adiponectin-expressing thymic Treg for adoptive immunotherapy in obesity and metabolic diseases
996,285.00
31/07/2020
30/07/2023
Dr. Yu WANG
RGF (1233576)
Roles of FGF21 signaling pathways in conferring the beneficial effects of physical exercise on cardiac metabolism and function in diabetic hearts
445,157.67
31/12/2018
30/12/2021
Prof. Aimin XU
Platform Technology Funding (PTF)
An advanced monoclonal antibody platform for biopharmaceutical development, medical diagnosis and precision medicine
723,115.00
29/06/2019
28/06/2021
Prof. Aimin XU
HMRF (06172446)
Autotaxin as a potential mediator of obesity-related metabolic complications
1,496,996.00
14/07/2019
13/07/2022
Prof. Aimin XU

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