生物醫藥技術國家重點實驗室
(香港大學)
State Key Laboratory of Pharmaceutical Biotechnology
(The University of Hong Kong)
Innovative Diagnostic Assay Platform
Simoa HD-X Analyzer
The SIMOA digital detection system can detect single molecule in bloodstream. The Simoa HD-X enables best-in-class assay performance for quantification of protein biomarkers in small volumes of serum, plasma or cerebrospinal fluid. A broad menu of single- and multi-plex assays are available across several areas of medical research, including neurology, oncology, cardiology, inflammation and infectious disease.
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To trap single protein molecules with first-class class antibodies coupled to paramagnetic beads in femtolitre-sized wells.
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the sensitivity of Simoa HD-X assays can be 1000 times greater than conventional immunoassays.
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Previously undetectable quantities of proteins are able to be accurately measured.
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Reproducibility of the Simoa HD-X is unmatched, with intra- and inter-assay coefficient of variation typically less than 5%.
All enquiries are welcome to Jiang Xue (xue0129@hku.hk) at 852 3502 2780
Meso Scale Discovery (MSD) High Performance Biomarker Assays and Services
MSD’s products are based on MULTI-ARRAY technology, a unique combination of electrochemiluminescence (ECL) detection, and patterned arrays. MSD Assays Offer a Broad Linear Range and a High Degree of Matrix Tolerance.
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Multiplex up to 10 analytes
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Wider dynamic range
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Higher sensitivity
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Lower sample volume
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Less matrix interference
All enquiries are welcome to Jiang Xue (xue0129@hku.hk) at 852 3502 2780
BS120 Automatic Biochemical Analyzer (Mindray)
A bench-top analyzer for clinical biochemical analysis and biochemical reagents development.
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Automatic dilution system.
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37 °C incubation.
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Test speed: 100 test/hour.
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8 different wavelengths.
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Minimum reaction volume: 180 μl.
All enquiries are welcome to Yue Hu (alexhy@hku.hk)
Synergy H1 Hybrid Microplate Reader (BioTek)
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Excellent plate reader: reliable, fast, good sensitivity.
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Monochromator absorbance.
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Full-light luminescence.
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Fluorescence polarization.
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Time resolved fluorescence.
All enquiries are welcome to Yue Hu (alexhy@hku.hk)
XF Extracellular Flux Analyzers (Seahorse)
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In vitro measurement of oxygen consumption, glycolysis, carbon dioxide, mitochondrial function, and fatty acid oxidation.
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Effect of oxidative stress on mitochondrial functions.
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Test the capacity of cells to maintain ATP level upon treatment with mitochondrial respiration inhibitor or glycolytic inhibitor.
All enquiries are welcome to Baile WANG (blwong@connect.hku.hk)
Anaerobic Chamber (DWS DG250)
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The workstation is used to process, culture and examine anaerobic samples without exposure to atmospheric oxygen.
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The workstation can accommodate 270 x 90mm Petri dishes.
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Temperature control: 5°C-45°C.
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The user portholes act as two mini-airlocks so the users can transfer plates at the same time as entering/exiting the workstation.
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The workstation is available with automatic sleeve gassing system operated by foot-switch so the users can ensure the correct conditions and use gas supplies efficiently.
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Gas supplies: 100% N2 and mix gas (10% H2 10% CO2 80% N2).
All enquiries are welcome to Jianyu Yao (jyyao@hku.hk) at 53720954
Multi-Channel Oxytherm System (Hansatech)
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For real-time measurement of oxygen signals in isolated mitochondria and cells
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User-friendly O2 data acquisition and system configuration software /li>
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8 channels which enables simultaneous measurement of multiple samples
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Suitable for examination of mitochondria respiration and function
All enquiries are welcome to Baile WANG (blwong@connect.hku.hk)